I hear it all the time "Our air is great down here but upstairs just sucks" I always offer to access and quote for additional Cooling for the upstairs. What other options to check out could be in play??
I have installed multiple zoned systems along with new duct systems and can have the upstairs colder than the downstairs on a 95* day. If your duct is designed right and you have figured out the load requirements you can heat/cool the space you are trying to condition. It can be done with proper design and implementation.